I am a Senior Research Fellow in the Department of Biochemistry, University of Cambridge and Consultant Cardiologist at Papworth Hospital, Cambridge. I have specialist interests in the investigation and management of arrhythmias with a large clinical practice. In addition, over the last several years my research group in Cambridge has gained a focus on a detailed characterization of the properties of the heart that provide the so-called ‘substrate’ for arrhythmias. The central, simple hypothesis that drives the work is that the determinants for the clinical risk of arrhythmias and sudden cardiac death (SCD) reside within the heart itself and much of this has a genetic basis. The core of the programme is to link the genetic alterations determining SCD to the observed arrhythmogenic phenotypes and relies on genetically modified mouse models.
I have a track record of publishing high quality research in both specialist and non-specialist journals; I attract funding from research organizations including the MRC, Wellcome Trust and the BHF. My work is known and respected internationally and I am regularly invited to participate in international research initiatives and conferences and contribute to the scientific literature. The BSCR provides an important voice arguing for the translation of ideas between basic science and clinical practice and I am glad of the opportunity to contribute.
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